Strategies to Use Nanofiber Scaffolds as Enzyme-Based Biocatalysts in Tissue Engineering Applications

Nanofibers are considered versatile materials with remarkable potential in tissue engineering and regeneration. In addition to their extracellular matrix-mimicking properties, nanofibers can be functionalized specific moieties (e.g., antimicrobial nanoparticles, ceramics, bioactive proteins, etc.) improve overall performance. A novel approach this regard is the use of enzymes immobilized onto impart biocatalytic activity. These capable carrying out catalysis various biological processes that essential healing process tissue. review, we emphasize regeneration applications. Biocatalytic used for wound edge or scar matrix digestion, which reduces hindrance cell migration proliferation, hence displaying applications fast repair, e.g., spinal cord injury. have bone regeneration, mediating osteogenic differentiation, biomineralization, formation through direct enzyme Moreover, undertake efficient crosslinking fabrication better physicochemical properties potential.